In a letter to denture cream manufactures, the U.S. Food & Drug Administration (FDA) recently acknowledged the risk of zinc poisoning associated with denture cream usage. The FDA states:
There are literature and research that suggest that zinc contained in some denture adhesives may be a contributing factor in these adverse events. Although zinc is an essential nutrient, overexposure may result in zinc toxicity. We are notifying all manufacturers of denture adhesives and asking for their assistance in dealing with this public health issue.
The manufacturers were asked to take steps to mitigate the risk of zinc poisoning with their products. Here's the Denture Cream Notice and Recommend Action Letter.